https://gastroenterology.acponline.org/archives/2025/11/21/7.htm

Case reports examine infection, other GI topics

Whipple disease, cutaneous gangrene in ulcerative colitis, and emphysematous pancreatitis were described recently.


Gastroenterology topics were covered in recent case reports in Annals of Internal Medicine: Clinical Cases.

One case report discussed an atypical case of Whipple disease with mesenteric lymphadenopathy and an exudative pleural effusion in a 62-year-old man who presented with a one-month history of unintentional weight loss, progressive nausea, abdominal pain, and intermittent nonbloody, nonbilious vomiting. It was published Oct. 21.

Another case report, published Nov. 4, described a 25-year-old man who presented with abdominal pain and hematochezia and was confirmed to have ulcerative colitis after colonoscopy biopsies. He developed thrombotic cutaneous gangrene during his hospitalization and eventually required amputation of his toes several months after discharge.

The final case report, also published Nov. 4, covered a rare case of emphysematous pancreatitis complicated by hemoperitoneum and abdominal compartment syndrome in a 54-year-old man with a history of alcohol use. He was treated with drainage, antibiotics, and eventual surgical debridement.