In the News
Global group offers recommendations on IBD at all stages of pregnancy
A global consensus statement on the management of pregnancy in inflammatory bowel disease (IBD) provides advice on how to manage medications and reduce risk of complications, among other topics.
Daily aspirin was associated with reduced colorectal cancer recurrence in patients with genetic mutations
Among patients with alterations in PI3K pathway genes and a history of colorectal cancer, the estimated three-year cumulative recurrence rate was 7.7% in those who took daily low-dose aspirin compared with 14.1% in controls, a Scandinavian trial found.
Antibiotic prophylaxis appears to reduce risk of infectious complications of ERCP
However, antibiotic prophylaxis in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) was not associated with improvements in mortality or pancreatitis rates, a review of 11 randomized trials found.
MKSAP Quiz: Hospitalized with gallstone pancreatitis
A 42-year-old patient is evaluated in the hospital 2 days after admission for gallstone pancreatitis. After initial treatment, a physical exam, and lab studies, what is the most appropriate management?
Spotlight on avoidant/restrictive eating
Recent studies evaluated how avoidant/restrictive eating may be related to disorders of gut-brain interaction and bowel symptoms.
Rare metastases of squamous-cell carcinoma, leiomyosarcoma described
Another recent case report discussed percutaneous cecostomy for symptom control in malignant bowel obstruction.
In MASH with moderate or advanced liver fibrosis, weekly semaglutide improved histologic steatohepatitis and fibrosis at 72 wk
The results of this interim analysis of a randomized trial are encouraging, but more data are needed on cirrhosis-free survival, liver-related events, and mortality in metabolic dysfunction-associated steatohepatitis (MASH), an ACP Journal Club commentary said.
CRC screening completion not improved by personalizing risk info
Randomly assigning patients to decision aids and clinicians to screening notifications with and without personalized messages about individual patient risk did not appear to affect completion of screening for colorectal cancer (CRC) at six months, a trial found.
Topical corticosteroids linked to peptic ulcer risk
Patients using long-term topical corticosteroids for atopic dermatitis were at significantly higher risk for upper GI complications, especially if they were also taking systemic corticosteroids, NSAIDs, or aspirin, a study in Taiwan found.
H. pylori screening following myocardial infarction does not reduce upper GI bleeding risk
Helicobacter pylori screening was associated with a lower risk of upper GI bleeding in patients with acute myocardial infarction who had moderate to severe anemia or kidney failure, suggesting that certain high-risk subgroups might benefit from targeted testing, the authors of a Swedish trial observed.