https://gastroenterology.acponline.org/archives/2025/02/28/6.htm

Handling H. pylori resistance

Antibiotic resistance and a new guideline will change how physicians manage Helicobacter pylori.


A cover story in the February I.M. Matters from ACP reported on the American College of Gastroenterology's updated guideline on treatment of Helicobacter pylori infection, detailing why optimized bismuth quadruple therapy is now preferred over triple therapy with a proton-pump inhibitor, clarithromycin or levofloxacin, and amoxicillin. Experts also explained why physicians should not separate H. pylori testing and treatment and offered advice on management and next steps.