Case reports cover drug-related GI and liver issues
Turmeric-induced liver injury, azithromycin-induced liver injury, and drug reaction with eosinophilia and systemic symptoms triggered by topical diclofenac were recently discussed.
Three case reports involving gastroenterology and hepatology were recently published by Annals of Internal Medicine: Clinical Cases.
The first report, published on Nov. 21, described a 36-year-old woman who presented with three weeks of progressive painless jaundice and pruritis and was found to have liver injury related to use of over-the-counter turmeric.
In the second report, published Dec. 5, drug reaction with eosinophilia and systemic symptoms (DRESS) with eosinophilic cholecystitis was triggered by topical diclofenac in a 64-year-old man who presented with a diffuse rash, abdominal fullness, and anorexia. The third report was also published Dec. 5 and described severe azithromycin-induced liver injury with vanishing bile duct syndrome necessitating liver transplantation in a 76-year-old man.