Current Issue
FMT appears safe, effective for recurrent C. diff in immunocompromised patients
Patients with mild to moderate immunocompromise and recurrent Clostridioides difficile infection had similar outcomes to immunocompetent patients after fecal microbiota transplantation (FMT), according to a systematic review and meta-analysis.
Cancer, decompensation more likely in men with cirrhosis than women
Men with cirrhosis had more than double the risk of hepatocellular carcinoma, a 63% higher risk of liver transplant, and a 16% higher risk of decompensated cirrhosis than women with the disease, and the differences were greatest in those with alcohol-related disease, a study found.
Shorter treatment possible for HCV, phase 2 study finds
Four weeks of daily glecaprevir and pibrentasvir resulted in sustained virologic response at 12 weeks in 84% of patients with early hepatitis C virus (HCV) infection, a study found.
MKSAP Quiz: Follow-up for chronic hepatitis C
A 65-year-old man is evaluated for follow-up of chronic hepatitis C virus infection, which was diagnosed more than 20 years ago and treated 2 years ago. He is asymptomatic. Following a physical exam, lab studies, and an ultrasound, what is the most appropriate test to perform next for further evaluation of this patient's liver disease?
Spotlight on IBD's associations with other diseases
One study found that patients with inflammatory bowel disease (IBD) have elevated risk of interstitial lung diseases, while another focused on the relationship of IBD and primary sclerosing cholangitis with increased risk of colorectal cancer.
In the Clinic: Irritable bowel syndrome
An In the Clinic article provided an overview of irritable bowel syndrome, a GI disorder with a prevalence of 4% to 10%.
Case reports discuss hematochezia, Sweet syndrome
One case focuses on hematochezia due to geophagia, while the other describes a patient with recalcitrant gut and cutaneous Sweet syndrome.
Colorectal cancer screening rising in younger populations
Three new studies looked at the rates, types, and results of colorectal cancer screening in patients ages 45 to 49 years in recent years.