Search results for "Clostridium difficile infection"
Intensive fecal microbiota transplant may improve outcomes in active ulcerative colitis
Researchers at three Australian hospitals assigned patients with active ulcerative colitis to receive fecal microbiota transplant infusions from three to seven unrelated donors or placebo infusions.
https://gastroenterology.acponline.org/archives/2017/02/24/1.htm
24 Feb 2017
In uncomplicated, left-sided acute diverticulitis, observation did not differ from antibiotics for recovery
At 6-month follow-up, no differences were found in time to recovery, readmission, development of complications, or mortality in patients assigned to observation or those assigned to antibiotics.
https://gastroenterology.acponline.org/archives/2017/02/24/7.htm
24 Feb 2017
Spotlight on gastric acid suppressants
Use of gastric acid suppressants was linked with increased risk of recurrent Clostridium difficile infection and of first-time ischemic stroke in recent research.
https://gastroenterology.acponline.org/archives/2017/04/28/5.htm
28 Apr 2017
In C difficile infection, adding IV bezlotoxumab to standard antibiotics reduced recurrence at 12 weeks
A commentary in ACP Journal Club noted that it would be reasonable to consider fidaxomicin or bezlotoxumab in patients at high risk for recurrent Clostridium difficile infection or in those for whom recurrence could have devastating consequences.
https://gastroenterology.acponline.org/archives/2017/05/26/10.htm
26 May 2017
Facility-level antibiotic use associated with C. difficile rates in long-term care
Importation of Clostridium difficile was three times more common in long-term care than in acute care, leading the study authors to recommend better coordination of infection control across settings.
https://gastroenterology.acponline.org/archives/2017/06/23/7.htm
23 Jun 2017
Recurrent C. difficile infections more than doubled between 2001 and 2012
Risk factors for recurrence include age; sex; and use of antibiotics, proton-pump inhibitors, or corticosteroids. These factors could adjust treatment algorithms for high-risk patients, including earlier use of fecal transplant.
https://gastroenterology.acponline.org/archives/2017/07/28/7.htm
28 Jul 2017
Antibiotic stewardship programs reduce incidence of C. difficile, multidrug-resistant infections, review finds
The systematic review also found that antibiotic stewardship programs were significantly more effective when implemented along with infection control measures.
https://gastroenterology.acponline.org/archives/2017/07/28/12.htm
28 Jul 2017
MKSAP quiz: Evaluation for Crohn disease flare
This month's quiz asks readers to determine the most appropriate treatment in a 22-year-old pregnant woman evaluated for a flare of Crohn disease.
https://gastroenterology.acponline.org/archives/2017/09/22/4.htm
22 Sep 2017
Fecal transplants by pill noninferior to colonoscopy delivery
The primary outcome of the unblinded, randomized trial was the proportion of patients without recurrent Clostridium difficile infection 12 weeks after fecal transplant.
https://gastroenterology.acponline.org/archives/2017/12/22/1.htm
22 Dec 2017
Updated guidelines for C. diff infection address fecal transplant, laboratory testing
The guidelines recommend laboratory testing for C. diff only in patients with new-onset, unexplained diarrhea, defined as at least three unformed stools in 24 hours, among other guidance.
https://gastroenterology.acponline.org/archives/2018/02/23/1.htm
23 Feb 2018