Current Issue


Semaglutide showed some benefit in patients with NASH, liver fibrosis

Significantly more patients taking the glucagon-like peptide-1 receptor agonist had resolution of their nonalcoholic steatohepatitis (NASH) than those taking placebo, but rates of liver fibrosis improvement were similar between groups, an industry-funded trial found.

Colonoscopy surveillance every 3 years may be sufficient after polypectomy

A multicenter randomized trial in Japan found that a single surveillance colonoscopy three years postpolypectomy and two surveillance colonoscopies at one and three years were similarly accurate for detecting clinically important neoplastic lesions.

Model that blends machine learning, traditional risk score may improve cirrhosis prediction

Using clinical variables identified from simple machine learning in a cirrhosis mortality model produced a new score that was more transparent than a commonly used version of the Model for End-Stage Liver Disease, a study found.

MKSAP Quiz: Treatment of diarrhea and abdominal pain

This month's quiz asks readers to determine the most appropriate treatment for a 35-year-old man with a one-year history of diarrhea and abdominal cramping and bloating.

Spotlight on The Liver Meeting

Highlights from the American Association for the Study of Liver Diseases' annual meeting, held virtually this past weekend, included insights on COVID-19 and the liver and a conversation with the winners of the Nobel Prize in Physiology or Medicine 2020, who discovered hepatitis C virus.

USPSTF draft recommendations favor screening younger patients for colorectal cancer

The U.S. Preventive Services Task Force (USPSTF) newly issued a B recommendation in support of screening adults ages 45 to 49 years. The recommendations are currently open for public comment.

Long-term survival did not differ with laparoscopic vs. open liver surgery in metastatic colon cancer

In a single-center randomized trial in Norway, five-year rates of overall and recurrence-free survival were 54% versus 55% and 30% versus 36%, respectively, in patients who received laparoscopic versus open surgery.