Researchers in the Netherlands performed a systematic review and meta-analysis of studies that compared fecal immunochemical test (FIT) results in average-risk patients who were taking oral anticoagulants or aspirin/NSAIDs versus those who were not taking the drugs.
Participants who had circulating vitamin D levels under 30 nmol/L had a 31% higher risk of colorectal cancer compared to those with levels between 50 and 62.5 nmol/L.
It is the first oral medication to be approved for chronic use in this population.
Clinicians should closely monitor patients with intragastric balloons for complications and explain symptoms that could be signs of serious or life-threatening problems, the FDA advised.
Adults should be screened with either a high-sensitivity stool-based test or a structural (visual) examination, depending on patient preference and test availability, the guideline said.
The retrospective study included 70,093 ICU patients who had at least one risk factor for stress ulcers and therefore had received a proton-pump inhibitor (PPI) or histamine H2-receptor antagonist (H2 blocker) for three or more days.