Current Issue


Drinking coffee may reduce risk of death, disease progression in patients with advanced colorectal cancer, study finds

An editorial noted coffee's unique role in diet, as it is widely consumed as a daily habit, and explained why a potential link between coffee consumption and colorectal cancer is biologically plausible.

AASLD offers guidance on reproductive health and liver disease

Menopausal hormone therapy should not be used in women with decompensated liver function, Budd-Chiari syndrome, or hepatocellular adenomas, the American Association for the Study of Liver Diseases (AASLD) said, among other recommendations.

Wireless monitoring identified patients who could discontinue PPIs

Patients with reflux symptoms and inadequate response to proton-pump inhibitors (PPIs) discontinued the drugs for a week and then had their acid exposure time measured by a wireless pH capsule in a recent study.

MKSAP Quiz: A 14-month history of diarrhea

This month's quiz asks readers to determine the most appropriate treatment for a 63-year-old woman with normal colonoscopy results who reports diarrhea multiple times per day, urge fecal incontinence, and nocturnal diarrhea.

Spotlight on HCV and organ transplants

Over the past month, multiple studies found that kidney and liver transplantation using organs from deceased donors with hepatitis C virus (HCV) infection may be effective in HCV-negative recipients treated with a direct-acting antiviral regimen.

Recent-onset diabetes, weight loss associated with increased pancreatic cancer risk

Unintentional weight loss and weight loss in those with a body mass index already in the normal range were particularly associated with risk of pancreatic cancer among patients with recent-onset diabetes, a study found.

Weight loss through gastric bypass or diet improved insulin sensitivity in patients with type 2 diabetes

Results from this small study suggest that reducing adipose tissue volume, by whatever means, will improve blood glucose control in patients with type 2 diabetes, an accompanying editorial noted.

COVID-19 outbreak linked to fecal aerosol transmission in one study

Nine COVID-19-positive patients from three families in China lived in vertically aligned apartments in the same building connected by drainage pipes in the master bathrooms.

H. pylori eradication therapy may reduce gastric cancer risk; rifabutin-based therapy effective in industry-sponsored trial

A meta-analysis suggested that, in addition to preventing progression, early Helicobacter pylori eradication therapy reduces gastric cancer risk, and a novel rifabutin-based therapy may offer physicians another option for initiating eradication treatment, an ACP Journal Club commentary on both studies said.