Current Issue


Pioglitazone associated with improved advanced fibrosis in patients with NASH

A recent meta-analysis looked at randomized clinical trials that examined the effect of thiazolidinediones on liver histology in patients with nonalcoholic steatohepatitis (NASH).

8 weeks of ledipasvir/sofosbuvir may be effective for genotype 1 hepatitis C

The therapy should be considered in patients with genotype 1 infection who are treatment-naive, do not have cirrhosis, and have a pretreatment viral load below 6,000,000 IU/mL, a study found.

GI bleeding less common in U.S. veterans on NOACs than those on warfarin

Significant bleeding occurred in 2.5% of the patients on warfarin and 0.6% of the patients on non-vitamin K antagonist oral anticoagulants (NOACs).

ACP Gastroenterology Monthly introduces editorial advisory board

ACP Gastroenterology Monthly is pleased to introduce its editorial advisory board.

MKSAP quiz: New-onset ascites with lower-extremity edema

What is the most likely cause of this 68-year-old man's ascites?

Spotlight on colorectal cancer

Studies this month looked at colorectal cancer screening, risk associated with dietary patterns, and estimated U.S. incidence.

High HCV cure rate seen with FDA-approved direct-acting antiviral regimens

Six of the direct-acting antiviral (DAA) regimens yielded sustained virologic response rates above 95% in patients who had hepatitis C virus (HCV) genotype 1 without cirrhosis, including those with HIV co-infection.

IBS-D drug should not be prescribed to patients without gallbladders

The FDA suggests that clinicians should consider alternatives to eluxadoline in this population.

New drug approved for carcinoid syndrome diarrhea

The drug reduces the frequency of diarrhea by inhibiting the production of serotonin by carcinoid tumors.

Physician editorial advisor: Minhhuyen T. Nguyen, MD, Fox Chase Cancer Center