Search results for "Irritable bowel syndrome"
Mesalamine moderately useful in IBS, but confidence in evidence is low
The authors of a recent meta-analysis wrote that guidelines for irritable bowel syndrome (IBS) management should not recommend the drug until adequately powered studies are available.
https://gastroenterology.acponline.org/archives/2023/03/24/3.htm
24 Mar 2023
In persons with constipation or IBS-C, kiwifruit vs. psyllium increased spontaneous bowel movements
Findings of the randomized trial bolster recommendations of diet manipulation and lifestyle modifications for chronic constipation syndromes, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2023/05/26/7.htm
26 May 2023
Low-dose amitriptyline appears effective as second-line treatment for IBS
Patients with irritable bowel syndrome (IBS) who were randomized to titrated doses of a tricyclic antidepressant had significant improvements in their IBS symptom scores at six months compared to those receiving a placebo, a trial in primary care found.
https://gastroenterology.acponline.org/archives/2023/10/27/2.htm
27 Oct 2023
Spotlight on gluten avoidance
An industry-funded trial of patients with self-reported gluten sensitivity found that symptoms were tied to the expectation of gluten more than actual consumption, while a study of celiac disease patients found that their symptoms often persisted after elimination of gluten.
https://gastroenterology.acponline.org/archives/2023/12/22/5.htm
22 Dec 2023
MKSAP Quiz: 3-month history of epigastric pain
A 40-year-old woman is evaluated for a 3-month history of epigastric pain, bloating, abdominal fullness, nausea, and diarrhea 30 to 60 minutes after meals that is worse with larger meals. Following a physical exam and other tests, what is the most appropriate treatment?
https://gastroenterology.acponline.org/archives/2024/01/26/4.htm
26 Jan 2024
In primary care, second-line IBS therapy with amitriptyline vs. placebo reduced symptoms at 6 mo
An ACP Journal Club commentary said the high-quality randomized trial provides pragmatic guidance on amitriptyline dosing in patients with irritable bowel syndrome (IBS), as well as additional support for the drug as an option in primary care after first-line therapies fail.
https://gastroenterology.acponline.org/archives/2024/02/23/7.htm
23 Feb 2024
In the Clinic, 2023 summary highlight gastroenterology topics
Colorectal cancer screening was the focus of the latest In the Clinic article, while an article in a supplement to Annals reviewed clinically important developments in gastroenterology and hepatology in 2023.
https://gastroenterology.acponline.org/archives/2024/04/26/5.htm
26 Apr 2024