Search results for "Highlights"
Guidance issued on pharmacologic treatment of chronic idiopathic constipation
The joint clinical practice guideline from the American Gastroenterological Association and the American College of Gastroenterology reviewed evidence on fiber, osmotic laxatives, stimulant laxatives, secretagogues, and a serotonin type 4 agonist.
https://gastroenterology.acponline.org/archives/2023/05/26/1.htm
26 May 2023
Defensiveness may help explain limited uptake of FIT, Irish study finds
Patients who declined an invitation to fecal immunochemical testing (FIT) scored higher on a measure of defensive information processing, indicating that certain psychological approaches may be more likely to increase screening uptake.
https://gastroenterology.acponline.org/archives/2023/02/24/2.htm
24 Feb 2023
Rates of pancreatic cancer rising, particularly among younger women
Among women ages 15 to 34 years, pancreatic cancer incidence rates rose by 6.45% per year in 2001 to 2018, according to a study using nationwide data covering about two-thirds of the U.S. population.
https://gastroenterology.acponline.org/archives/2023/02/24/3.htm
24 Feb 2023
Review examines drugs, lifestyle treatments for NAFLD
The umbrella review included 27 meta-analyses of randomized controlled trials examining the effectiveness of pharmacological interventions and lifestyle modifications, including diet and exercise, for patients with nonalcoholic fatty liver disease (NAFLD).
https://gastroenterology.acponline.org/archives/2022/05/27/2.htm
27 May 2022
In adults using oral anticoagulants, PPI use may be associated with lower risk for upper GI bleeding
An ACP Journal Club commentary on the meta-analysis stressed the importance of assessing patients' underlying risk for GI bleeding and using overall clinical risk to guide shared decision making in those at higher risk or with lower baseline bleeding tolerance.
https://gastroenterology.acponline.org/archives/2022/11/18/9.htm
18 Nov 2022
Fatty liver disease may not affect mortality risk in elderly patients
In a Dutch cohort study of patients ages 65 years and older, no association was found between hepatic steatosis and death in the overall population or in clinically relevant subgroups.
https://gastroenterology.acponline.org/archives/2022/07/22/3.htm
22 Jul 2022
Guidance offered on management of extraesophageal GERD
The clinical practice update from the American Gastroenterological Association was based on a review of the evidence and expert opinion regarding extraesophageal symptoms of gastroesophageal reflux disease (GERD).
https://gastroenterology.acponline.org/archives/2023/04/21/2.htm
21 Apr 2023
DPP-4 inhibitors associated with risk of cholecystitis, meta-analysis finds
Patients with type 2 diabetes who were randomized to receive dipeptidyl peptidase-4 (DPP-4) inhibitors had higher rates of gallbladder disease than those who got placebo or nonincretin drugs, but no difference in risk of cholelithiasis or biliary diseases.
https://gastroenterology.acponline.org/archives/2022/07/22/6.htm
22 Jul 2022
EoE patients with high BMI may be less likely to respond to topical corticosteroids
A retrospective cohort study of patients with eosinophilic esophagitis (EoE) found that each 1-point increase in body mass index (BMI) was associated with a 7% decrease in odds of histologic response to topical corticosteroids and that patients with obesity had about 40% odds of responding compared to those without.
https://gastroenterology.acponline.org/archives/2022/12/23/2.htm
23 Dec 2022
IV iron regimens compared for serum phosphate effects in patients with IBD
Ferric carboxymaltose and ferric derisomaltose worked well to resolve anemia from inflammatory bowel disease (IBD), but the former was associated with low serum phosphate levels, according to an industry-funded trial.
https://gastroenterology.acponline.org/archives/2022/09/23/2.htm
23 Sep 2022