Search results for "Highlights"
Drinking coffee may reduce risk of death, disease progression in patients with advanced colorectal cancer, study finds
An editorial noted coffee's unique role in diet, as it is widely consumed as a daily habit, and explained why a potential link between coffee consumption and colorectal cancer is biologically plausible.
https://gastroenterology.acponline.org/archives/2020/09/25/1.htm
25 Sep 2020
Semaglutide showed some benefit in patients with NASH, liver fibrosis
Significantly more patients taking the glucagon-like peptide-1 receptor agonist had resolution of their nonalcoholic steatohepatitis (NASH) than those taking placebo, but rates of liver fibrosis improvement were similar between groups, an industry-funded trial found.
https://gastroenterology.acponline.org/archives/2020/11/20/1.htm
20 Nov 2020
Study finds higher proportion of CRC diagnoses in patients under 50 since 2004
Based on the results, study authors suggested expanding colorectal cancer (CRC) screening to patients 45 years of age, but an accompanying editorial expressed concern that the risks could outweigh the benefits in the general population.
https://gastroenterology.acponline.org/archives/2019/07/26/2.htm
26 Jul 2019
Anti-TNF therapy did not reduce IBD hospitalizations or intestinal resections in Ontario
Infliximab may have been used inappropriately in Crohn's disease and underused in ulcerative colitis, according to the authors of an analysis of hospitalizations, intestinal resections, and drug costs related to inflammatory bowel disease (IBD).
https://gastroenterology.acponline.org/archives/2019/06/28/3.htm
28 Jun 2019
Liver function tests at admission could help predict mortality from COVID-19
Elevations in aspartate aminotransferase and direct bilirubin levels were significantly more common among patients in China who died of COVID-19 than those who survived to hospital discharge, a retrospective study found.
https://gastroenterology.acponline.org/archives/2021/01/22/1.htm
22 Jan 2021
Combination therapy for IBD carries higher infection risk than monotherapy
Monotherapy for inflammatory bowel disease (IBD) with an immunosuppressive agent was associated with a lower risk of serious infection than a tumor necrosis factor (TNF) antagonist alone or an anti-TNF plus an immunosuppressive agent, according to a meta-analysis.
https://gastroenterology.acponline.org/archives/2019/03/22/2.htm
22 Mar 2019
Effects of gastric acid suppression drugs on COVID-19 outcomes still unclear
A meta-analysis didn't find an association between famotidine use and severe disease or death from COVID-19, and the association of these outcomes with proton-pump inhibitors varied by study type.
https://gastroenterology.acponline.org/archives/2021/02/26/1.htm
26 Feb 2021
Antidepressants and psychological therapies reduce IBS symptoms, meta-analysis finds
Psychological therapies were effective for irritable bowel syndrome (IBS) when delivered in person, whereas therapy that was self-administered, internet-based, or provided with minimal contact did not yield significant benefit.
https://gastroenterology.acponline.org/archives/2018/09/28/2.htm
28 Sep 2018
Beta-blockers linked to better outcomes in some patients with cirrhosis
Decompensation-free survival improved in patients with cirrhosis and portal hypertension who received beta-blockers versus placebo, largely due to a decrease in ascites.
https://gastroenterology.acponline.org/archives/2019/04/26/3.htm
26 Apr 2019
Use of drugs, nondrug treatments for functional bowel disorders analyzed
One study found that nonpharmacologic interventions are underused in ambulatory care visits for functional bowel disorders, while another found that patients with irritable bowel disease and their insurers have financial incentives to favor differing treatments.
https://gastroenterology.acponline.org/archives/2020/10/23/1.htm
23 Oct 2020