Search results for "Constipation"
Drug for chronic idiopathic constipation approved
The oral medication is taken once per day and works in the upper GI tract to stimulate secretion of intestinal fluid, supporting regular bowel function.
https://gastroenterology.acponline.org/archives/2017/01/27/7.htm
27 Jan 2017
In chronic severe functional constipation, electroacupuncture increased complete spontaneous bowel movements
Patients undergoing electroacupuncture experienced a change from baseline in mean complete spontaneous bowel movements per week during the treatment period, and treatment effects were even greater after patients stopped attending the sessions.
https://gastroenterology.acponline.org/archives/2017/01/27/9.htm
27 Jan 2017
New drug approved for carcinoid syndrome diarrhea
The drug reduces the frequency of diarrhea by inhibiting the production of serotonin by carcinoid tumors.
https://gastroenterology.acponline.org/archives/2017/03/24/9.htm
24 Mar 2017
Spotlight on FODMAPs
Two studies published this month, a review and a randomized, placebo-controlled trial, looked at the impact of a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) in patients with irritable bowel syndrome.
https://gastroenterology.acponline.org/archives/2017/06/23/5.htm
23 Jun 2017
Mu-opioid receptor antagonists appear safe, effective for opioid-induced constipation, review finds
Researchers looked at randomized controlled trials of peripheral mu-opioid receptor antagonists (methylnaltrexone, naloxone, naloxegol, alvimopan, axelopran, or naldemedine) and the prescription-strength laxatives lubiprostone or prucalopride.
https://gastroenterology.acponline.org/archives/2018/02/23/2.htm
23 Feb 2018
Guidance issued on evaluation, treatment of hemorrhoids
Primary first-line therapy for patients with symptomatic hemorrhoid disease should typically include dietary modification to ensure adequate fluid and fiber intake and counseling on defecation habits, the guidelines said.
https://gastroenterology.acponline.org/archives/2018/03/23/8.htm
23 Mar 2018
Drug options available for opioid-induced constipation
Four FDA-approved drugs for opioid-induced constipation form the backbone of treatment, with more options in the research pipeline.
https://gastroenterology.acponline.org/archives/2018/04/27/7.htm
27 Apr 2018
Naloxone, naldemedine appear best for opioid-induced constipation after laxatives
A meta-analysis found naloxone to have the highest efficacy and safety of pharmacological therapies for opioid-induced constipation, and previous research has shown it to be cost-effective, study authors said.
https://gastroenterology.acponline.org/archives/2018/05/25/1.htm
25 May 2018
MKSAP quiz: Long-term refractory constipation
This month's quiz asks readers to determine the most appropriate management for a 36-year-old woman with a 12-year history of refractory constipation that began after a difficult childbirth.
https://gastroenterology.acponline.org/archives/2018/06/22/3.htm
22 Jun 2018
In IBS with constipation, plecanatide reduced abdominal pain and increased bowel movements at 12 wk
Clinical judgment will be needed to determine whether the relatively modest improvement in outcomes will be important to patients for whom the drug is considered, according to an accompanying ACP Journal Club commentary.
https://gastroenterology.acponline.org/archives/2018/07/27/9.htm
27 Jul 2018