Search results for "Highlights"
PPI use in the ICU associated with mortality risk
A systematic review and meta-analysis found that critically ill patients who received proton-pump inhibitors (PPIs) versus any comparator for stress ulcer prophylaxis had a higher risk for death, especially if they were more severely ill at baseline.
https://gastroenterology.acponline.org/archives/2022/06/24/3.htm
24 Jun 2022
Guidance offered on management of extraesophageal GERD
The clinical practice update from the American Gastroenterological Association was based on a review of the evidence and expert opinion regarding extraesophageal symptoms of gastroesophageal reflux disease (GERD).
https://gastroenterology.acponline.org/archives/2023/04/21/2.htm
21 Apr 2023
Review finds only two efficacious medications to treat gastroparesis
Clebopride ranked first for efficacy, followed by domperidone, and no other drug was superior to placebo for improving symptoms of gastroparesis, according to a recent meta-analysis.
https://gastroenterology.acponline.org/archives/2023/01/27/2.htm
27 Jan 2023
Guidance issued on pharmacologic treatment of chronic idiopathic constipation
The joint clinical practice guideline from the American Gastroenterological Association and the American College of Gastroenterology reviewed evidence on fiber, osmotic laxatives, stimulant laxatives, secretagogues, and a serotonin type 4 agonist.
https://gastroenterology.acponline.org/archives/2023/05/26/1.htm
26 May 2023
Review examines drugs, lifestyle treatments for NAFLD
The umbrella review included 27 meta-analyses of randomized controlled trials examining the effectiveness of pharmacological interventions and lifestyle modifications, including diet and exercise, for patients with nonalcoholic fatty liver disease (NAFLD).
https://gastroenterology.acponline.org/archives/2022/05/27/2.htm
27 May 2022
AGA issues guidance on drug treatment for patients with IBS
Two new clinical practice guidelines from the American Gastroenterological Association (AGA) provide recommendations on the use of medications to treat irritable bowel syndrome (IBS) with constipation and IBS with diarrhea.
https://gastroenterology.acponline.org/archives/2022/06/24/1.htm
24 Jun 2022
In adults using oral anticoagulants, PPI use may be associated with lower risk for upper GI bleeding
An ACP Journal Club commentary on the meta-analysis stressed the importance of assessing patients' underlying risk for GI bleeding and using overall clinical risk to guide shared decision making in those at higher risk or with lower baseline bleeding tolerance.
https://gastroenterology.acponline.org/archives/2022/11/18/9.htm
18 Nov 2022
Risk for CRC with young-onset adenomas may vary by stage
A cohort study in U.S. veterans younger than age 50 years found that those with advanced adenomas had an eightfold increased risk for incident colorectal cancer (CRC) versus those with normal results, whereas cumulative CRC incidence and mortality at 10 years were relatively low overall.
https://gastroenterology.acponline.org/archives/2023/04/21/3.htm
21 Apr 2023
High consumption of ultra-processed foods associated with CRC in men
Among women, only consumption of ready-to-eat or -heat mixed dishes was linked to increased risk of colorectal cancer (CRC), according to a new analysis of the Health Professionals Follow-up Study and Nurses' Health Studies.
https://gastroenterology.acponline.org/archives/2022/09/23/3.htm
23 Sep 2022
Fatty liver disease may not affect mortality risk in elderly patients
In a Dutch cohort study of patients ages 65 years and older, no association was found between hepatic steatosis and death in the overall population or in clinically relevant subgroups.
https://gastroenterology.acponline.org/archives/2022/07/22/3.htm
22 Jul 2022