Search results for "GI bleeding"
Restricting PPI prescription refills reduced use without noticeable clinical effects
Restrictions on proton-pump inhibitor (PPI) refills for patients without a documented long-term indication were associated with a rapid and sustained 7.3% absolute reduction in such prescriptions—a relative decline of nearly 30%, a Veterans Affairs study found.
https://gastroenterology.acponline.org/archives/2024/04/26/1.htm
26 Apr 2024
Tranexamic acid may help with upper GI bleeding after esophageal variceal ligation
Tranexamic acid significantly reduced upper GI bleeding after esophageal variceal ligation, but mortality rates were similar to those with placebo, a trial in India found.
https://gastroenterology.acponline.org/archives/2024/03/22/3.htm
22 Mar 2024
Case report details serious, recurrent GI bleeding associated with sotatercept
The investigational medication is being evaluated for use in patients with pulmonary arterial hypertension.
https://gastroenterology.acponline.org/archives/2024/01/26/6.htm
26 Jan 2024
Spotlight on hospitalizations for cirrhosis
Recent studies looked at predicting readmissions, treating acute kidney injury, and improving health literacy in patients hospitalized with cirrhosis.
https://gastroenterology.acponline.org/archives/2023/08/25/5.htm
25 Aug 2023
Case reports, series published on gastroenterology, hepatology topics
Recent cases include massive empyema with Edwardsiella tarda in a patient with cirrhosis, paraneoplastic myositis in a patient with extrahepatic cholangiocarcinoma, and two patients with refractory iron deficiency anemia secondary to angiodysplasia-related GI bleeding.
https://gastroenterology.acponline.org/archives/2023/04/21/8.htm
21 Apr 2023
ACG updates its guideline on acute lower GI bleeding
The American College of Gastroenterology (ACG) now recommends risk stratification to identify patients who can be discharged early and advises on the use of anticoagulant reversal agents, among other changes.
https://gastroenterology.acponline.org/archives/2023/03/24/2.htm
24 Mar 2023
Over-the-scope clips may be better initial treatment than standard hemostatic treatment in patients with nonvariceal upper GI bleeding
In a randomized controlled trial of 190 adults, 30-day probability of further bleeding was significantly lower in patients who received over-the-scope clips than in those who received standard endoscopic hemostatic treatment.
https://gastroenterology.acponline.org/archives/2023/03/24/10.htm
24 Mar 2023
In adults using oral anticoagulants, PPI use may be associated with lower risk for upper GI bleeding
An ACP Journal Club commentary on the meta-analysis stressed the importance of assessing patients' underlying risk for GI bleeding and using overall clinical risk to guide shared decision making in those at higher risk or with lower baseline bleeding tolerance.
https://gastroenterology.acponline.org/archives/2022/11/18/9.htm
18 Nov 2022
Apixaban associated with lower risk of GI bleeding compared to other DOACs
Apixaban users experienced similar rates of ischemic stroke or systemic embolism, intracranial hemorrhage, and all-cause mortality as patients taking other direct oral anticoagulants (DOACs), a retrospective analysis found.
https://gastroenterology.acponline.org/archives/2022/11/18/6.htm
18 Nov 2022
GI bleeding risks with warfarin and DOACs compared
Warfarin was associated with a similar risk of lower GI bleeding as direct oral anticoagulants (DOACs) but more than twice the rate of upper GI bleeding, which led study authors to suggest that DOACs may be preferable to warfarin in patients at high risk of upper GI bleeds.
https://gastroenterology.acponline.org/archives/2022/08/26/1.htm
26 Aug 2022