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New international guideline updates recommendations on managing patients with nonvariceal GI bleeding

The new guideline is “a step forward,” particularly with regard to new endoscopic therapies and management of upper gastrointestinal (GI) bleeding in patients on antiplatelet or anticoagulant drugs, an editorial noted.
https://gastroenterology.acponline.org/archives/2019/10/25/6.htm
25 Oct 2019

C. diff-related bloodstream infection seen less often with FMT vs. antibiotics

While fecal microbiota transplantation (FMT) was associated with fewer bloodstream infections than antibiotics in one study, a brief report described two cases of drug-resistant bacteremia transmitted by FMT.
https://gastroenterology.acponline.org/archives/2019/11/22/9.htm
22 Nov 2019

GI bleeding prophylaxis recommended in high-risk critically ill patients

Proton-pump inhibitors appeared to reduce bleeding risk more than histamine-2 receptor antagonists.
https://gastroenterology.acponline.org/archives/2020/01/24/9.htm
24 Jan 2020

PPIs started for stress ulcer prophylaxis in critically ill patients often continued after ICU, hospital discharge

A study at one U.S. academic medical center found that nearly half of patients who started proton-pump inhibitors (PPIs) in the ICU without an indication for outpatient use continued them after transfer to the floor, and 27% continued them after discharge.
https://gastroenterology.acponline.org/archives/2020/12/18/7.htm
18 Dec 2020

Studies examine impact of hospital policies on C. difficile infection rates

While one study found that participation in an antibiotic stewardship program from the Agency for Healthcare Research and Quality led to reductions in hospital-onset Clostridioides difficile infection rates, a simulation study found that visitor contact precautions may not be as helpful.
https://gastroenterology.acponline.org/archives/2021/03/26/7.htm
26 Mar 2021

Problem of PPIs complicated by COVID-19

While recent studies have suggested that physicians should be careful when using proton-pump inhibitors (PPIs) in patients hospitalized with COVID-19, none have shown a causal relationship between PPIs and COVID-19 infection or severity.
https://gastroenterology.acponline.org/archives/2021/04/23/7.htm
23 Apr 2021

Immediate catheter drainage not superior to delayed in infected necrotizing pancreatitis

A trial found that catheter drainage within 24 hours was associated with similar complications but a greater number of interventions compared to drainage that was delayed until the development of walled-off necrosis.
https://gastroenterology.acponline.org/archives/2021/10/22/6.htm
22 Oct 2021

Computerized clinical decision support may help reduce unnecessary C. diff testing

A two-year cohort study of nine academic and six community hospitals in the U.S. found that testing for Clostridioides difficile decreased when the electronic health record stopped a clinician from proceeding with a test order if the patient had already been tested or had recently received laxatives.
https://gastroenterology.acponline.org/archives/2022/02/25/7.htm
25 Feb 2022

Manage meds to treat GI bleeding before, after endoscopy

Care of inpatients with GI bleeding is complicated and multidisciplinary, but hospitalists can contribute by starting and stopping the right drugs, according to conference coverage from Internal Medicine Meeting 2022.
https://gastroenterology.acponline.org/archives/2022/05/27/6.htm
27 May 2022

A click to improve cirrhosis care

An electronic alert increased use of rifaximin in patients with cirrhosis who were taking lactulose and were admitted with hepatic encephalopathy.
https://gastroenterology.acponline.org/archives/2022/06/24/7.htm
24 Jun 2022

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