A retrospective trial showed no increase in new corticosteroid therapy or disease-related hospitalization or surgery among patients who discontinued 5-aminosalycilate (5-ASA) therapy when initiating an anti-tumor necrosis factor (anti-TNF) agent.
Active choice interventions in an EHR prompted an increase in ordering of cancer screenings but not patient follow-through, while physicians who themselves underwent colorectal cancer (CRC) screening had more patients do so as well.
In a meta-analysis of 22 studies in patients with nonalcoholic fatty liver disease (NAFLD), weight loss interventions were associated with improvements in alanine aminotransferase level, liver steatosis, histologic NAFLD activity score, and
Based on the results, study authors suggested expanding colorectal cancer (CRC) screening to patients 45 years of age, but an accompanying editorial expressed concern that the risks could outweigh the benefits in the general population.
Included trials evaluated an exclusion diet versus an alternative or usual diet and assessed improvement in either global symptoms of irritable bowel syndrome (IBS) or abdominal pain.
An accompanying editorial said that based on the risk of gastrointestinal (GI) events found in this retrospective study, sodium polystyrene sulfonate should not be used to reduce serum potassium levels.
Infliximab may have been used inappropriately in Crohn's disease and underused in ulcerative colitis, according to the authors of an analysis of hospitalizations, intestinal resections, and drug costs related to inflammatory bowel disease (IBD).
Significant bleeding occurred in 2.5% of the patients on warfarin and 0.6% of the patients on non-vitamin K antagonist oral anticoagulants (NOACs).
A recent meta-analysis looked at randomized clinical trials that examined the effect of thiazolidinediones on liver histology in patients with nonalcoholic steatohepatitis (NASH).
The guidelines also highlight the importance of team-based care for these patients and enhanced recovery after bariatric surgery.