Search results for "Highlights"


 
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Boxed warning added to liver disease drug

The drug has been incorrectly dosed daily instead of weekly in patients with moderate to severe primary biliary cholangitis, which increases the risk of serious liver injury, the FDA said.
https://gastroenterology.acponline.org/archives/2018/02/23/7.htm
23 Feb 2018

Patients with mild acute diverticulitis can be safely treated without antibiotics in outpatient setting

Patients who presented to an ED and were randomized to receive only anti-inflammatory and symptomatic treatment had similar rates of hospitalization, return to the ED, and pain control as those who received the usual antibiotic treatment, a Spanish trial found.
https://gastroenterology.acponline.org/archives/2021/11/19/2.htm
19 Nov 2021

Rise in liver disease deaths not fully explained by metabolic syndrome or alcohol use

An analysis of the prevalence of metabolic syndrome and alcohol use in the U.S. between 1999 and 2018 found that while the proportion of patients with metabolic syndrome and nonheavy alcohol use grew the most, liver disease increased the most among those who drank heavily.
https://gastroenterology.acponline.org/archives/2023/05/26/3.htm
26 May 2023

Electronic alert about lactulose linked to lower readmissions in patients with cirrhosis

The alert, which encouraged clinicians to prescribe rifaximin for patients with cirrhosis and hepatic encephalopathy who were on lactulose, increased uptake of rifaximin in such patients.
https://gastroenterology.acponline.org/archives/2022/01/28/3.htm
28 Jan 2022

Safe to stop 5-ASA therapy for Crohn's disease when anti-TNF agent is started, study finds

A retrospective trial showed no increase in new corticosteroid therapy or disease-related hospitalization or surgery among patients who discontinued 5-aminosalycilate (5-ASA) therapy when initiating an anti-tumor necrosis factor (anti-TNF) agent.
https://gastroenterology.acponline.org/archives/2019/08/23/3.htm
23 Aug 2019

Clinical practice update focuses on belching, bloating, distention

The American Gastroenterological Association offered 15 best practices for physicians caring for patients with these common GI symptoms.
https://gastroenterology.acponline.org/archives/2023/07/28/1.htm
28 Jul 2023

Efficacy, safety of second-line therapies analyzed for two types of IBS

A systematic review and network meta-analysis focused on alosetron, eluxadoline, ramosetron, and rifaximin in adult patients who had irritable bowel syndrome (IBS) with diarrhea or mixed stool.
https://gastroenterology.acponline.org/archives/2019/04/26/2.htm
26 Apr 2019

PPI use in the ICU associated with mortality risk

A systematic review and meta-analysis found that critically ill patients who received proton-pump inhibitors (PPIs) versus any comparator for stress ulcer prophylaxis had a higher risk for death, especially if they were more severely ill at baseline.
https://gastroenterology.acponline.org/archives/2022/06/24/3.htm
24 Jun 2022

Cannabis, cannabinoids didn't improve remission or inflammatory markers in IBD

A meta-analysis of inflammatory bowel disease (IBD) studies did find improvements in patient-reported symptoms and quality of life associated with cannabis and cannabinoids.
https://gastroenterology.acponline.org/archives/2020/07/24/3.htm
24 Jul 2020

Practice guidance addresses vascular liver disorders, portal vein thrombosis, procedural bleeding

Among other statements, the American Association for the Study of Liver Diseases said that modifiable risk factors for bleeding, such as use of antithrombotic drugs, should be identified and corrected before procedures in patients with cirrhosis.
https://gastroenterology.acponline.org/archives/2020/12/18/2.htm
18 Dec 2020

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