Search results for "Highlights"
Spotlight on treatment response in Crohn's disease
Recent studies evaluated early versus late response to biologic therapy, treatment response and infection risk, and endoscopic outcomes.
https://gastroenterology.acponline.org/archives/2024/01/26/5.htm
26 Jan 2024
No-biopsy approach can diagnose celiac disease in select adults
IgA anti-tissue transglutaminase levels of at least 10 times the upper limit of normal have a sensitivity of 51% and specificity of 100% for predicting celiac disease in adults referred to secondary care, a meta-analysis found.
https://gastroenterology.acponline.org/archives/2024/01/26/1.htm
26 Jan 2024
Concurrent cholinesterase inhibitors, NSAIDs linked to peptic ulcer risk
Risk of peptic ulcers increased ninefold when patients ages 65 years and older took cholinesterase inhibitors and NSAIDs concurrently, a Swedish study found, leading the authors to suggest that the combination be considered potentially inappropriate for older patients.
https://gastroenterology.acponline.org/archives/2023/11/17/2.htm
17 Nov 2023
Tranexamic acid may help with upper GI bleeding after esophageal variceal ligation
Tranexamic acid significantly reduced upper GI bleeding after esophageal variceal ligation, but mortality rates were similar to those with placebo, a trial in India found.
https://gastroenterology.acponline.org/archives/2024/03/22/3.htm
22 Mar 2024
Review finds antibiotics associated with heightened risk of inflammatory bowel disease
There was a positive, nonlinear dose-response association between the number of antibiotic prescriptions patients received and their inflammatory bowel disease risk, according to a systematic review.
https://gastroenterology.acponline.org/archives/2024/03/22/2.htm
22 Mar 2024
Fenofibrate may augment treatment for primary biliary cholangitis
Adding fenofibrate to ursodeoxycholic acid significantly increased the likelihood of biochemical response and normalization of alkaline phosphatase levels, a small trial in China found.
https://gastroenterology.acponline.org/archives/2023/11/17/3.htm
17 Nov 2023
Medications for AUD appear beneficial in patients with cirrhosis
A systematic review and meta-analysis found that medications for alcohol use disorder (AUD) were associated with 32% more abstinence versus placebo or standard treatment in patients with alcohol-induced cirrhosis.
https://gastroenterology.acponline.org/archives/2023/09/22/1.htm
22 Sep 2023
Guideline newly recommends biomarkers to monitor Crohn's disease
The American Gastroenterological Association offered advice on using blood and stool tests to monitor inflammation and reduce the frequency of invasive endoscopy.
https://gastroenterology.acponline.org/archives/2023/12/22/1.htm
22 Dec 2023
Noninvasive methods show promise for CRC screening
A DNA blood-based test had approximately 83% sensitivity for colorectal cancer (CRC) and 13% sensitivity for advanced precancerous lesions in one industry-funded study, while a next-generation multitarget stool DNA test showed higher sensitivity but lower specificity for CRC and advanced precancerous lesions than fecal immunochemical testing in another.
https://gastroenterology.acponline.org/archives/2024/03/22/1.htm
22 Mar 2024
Alcohol abstinence not required for direct-acting antivirals to cure HCV, study finds
Restricting access to direct-acting antiviral therapy because of alcohol use creates an unnecessary barrier for patients with hepatitis C virus (HCV) infection, according to the authors of a recent study.
https://gastroenterology.acponline.org/archives/2023/10/27/1.htm
27 Oct 2023