In a meta-analysis of 22 studies in patients with nonalcoholic fatty liver disease (NAFLD), weight loss interventions were associated with improvements in alanine aminotransferase level, liver steatosis, histologic NAFLD activity score, and
Infliximab may have been used inappropriately in Crohn's disease and underused in ulcerative colitis, according to the authors of an analysis of hospitalizations, intestinal resections, and drug costs related to inflammatory bowel disease (IBD).
Guidelines currently recommend nonselective beta-blockers or variceal band ligation for primary prevention of variceal bleeding based on similar efficacy, but survival benefit may be better with the former treatment.
While the American College of Gastroenterology (ACG) included new recommendations for using fecal microbiota transplantation in recurrent Clostridioides difficile infection, it recommended against the use of probiotics for both primary and secondary
Based on the results, study authors suggested expanding colorectal cancer (CRC) screening to patients 45 years of age, but an accompanying editorial expressed concern that the risks could outweigh the benefits in the general population.
In 19 randomized controlled trials of 6,261 hospitalized patients on antibiotics, the incidence of C. difficile was 1.6% among patients taking probiotics compared to 3.9% in controls.
Monotherapy for inflammatory bowel disease (IBD) with an immunosuppressive agent was associated with a lower risk of serious infection than a tumor necrosis factor (TNF) antagonist alone or an anti-TNF plus an immunosuppressive agent, according to a
The guideline focuses on oral and topical 5-aminosalicylic acid medications, rectal corticosteroids, and oral budesonide in patients with mild to moderate disease.
A meta-analysis didn't find an association between famotidine use and severe disease or death from COVID-19, and the association of these outcomes with proton-pump inhibitors varied by study type.
Elevations in aspartate aminotransferase and direct bilirubin levels were significantly more common among patients in China who died of COVID-19 than those who survived to hospital discharge, a retrospective study found.