Search results for "Highlights"
Fenofibrate may augment treatment for primary biliary cholangitis
Adding fenofibrate to ursodeoxycholic acid significantly increased the likelihood of biochemical response and normalization of alkaline phosphatase levels, a small trial in China found.
https://gastroenterology.acponline.org/archives/2023/11/17/3.htm
17 Nov 2023
Guideline newly recommends biomarkers to monitor Crohn's disease
The American Gastroenterological Association offered advice on using blood and stool tests to monitor inflammation and reduce the frequency of invasive endoscopy.
https://gastroenterology.acponline.org/archives/2023/12/22/1.htm
22 Dec 2023
GLP-1 receptor agonists may affect colonoscopy bowel prep
A retrospective cohort study found that patients taking glucagon-like peptide-1 (GLP-1) receptor agonists for diabetes or obesity had lower-quality bowel prep for colonoscopy and were more likely to be called back for a repeat test.
https://gastroenterology.acponline.org/archives/2023/10/27/3.htm
27 Oct 2023
Low-dose amitriptyline appears effective as second-line treatment for IBS
Patients with irritable bowel syndrome (IBS) who were randomized to titrated doses of a tricyclic antidepressant had significant improvements in their IBS symptom scores at six months compared to those receiving a placebo, a trial in primary care found.
https://gastroenterology.acponline.org/archives/2023/10/27/2.htm
27 Oct 2023
Lack of follow-up common for rectal bleeding in primary care
A retrospective cohort study found that 22.3% of patients didn't get timely workup for rectal bleeding; among that cohort, 36% had no follow-up procedure ordered and 44% had one ordered but not scheduled or scheduled but not completed.
https://gastroenterology.acponline.org/archives/2023/11/17/1.htm
17 Nov 2023
Alcohol abstinence not required for direct-acting antivirals to cure HCV, study finds
Restricting access to direct-acting antiviral therapy because of alcohol use creates an unnecessary barrier for patients with hepatitis C virus (HCV) infection, according to the authors of a recent study.
https://gastroenterology.acponline.org/archives/2023/10/27/1.htm
27 Oct 2023
Phase 3 study offers evidence on drug dosing for eosinophilic esophagitis
Findings from an industry-funded study showed that using dupilumab weekly, rather than every two weeks, improved symptoms in adults and adolescents with eosinophilic esophagitis.
https://gastroenterology.acponline.org/archives/2023/09/22/2.htm
22 Sep 2023
Prophylactic antibiotics help prevent post-ERCP infections
A randomized trial in Korea found that patients with biliary obstruction who underwent endoscopic retrograde cholangiopancreatography (ERCP) were less likely to develop infection if they received antibiotics before the procedure.
https://gastroenterology.acponline.org/archives/2023/09/22/3.htm
22 Sep 2023
Medications for AUD appear beneficial in patients with cirrhosis
A systematic review and meta-analysis found that medications for alcohol use disorder (AUD) were associated with 32% more abstinence versus placebo or standard treatment in patients with alcohol-induced cirrhosis.
https://gastroenterology.acponline.org/archives/2023/09/22/1.htm
22 Sep 2023
IBD patients may be at higher risk for CKD
A Swedish study found that 11.8% of patients with inflammatory bowel disease (IBD) were diagnosed with chronic kidney disease (CKD) within 10 years, and their risks of acute kidney injury and kidney stones were also elevated.
https://gastroenterology.acponline.org/archives/2023/08/25/2.htm
25 Aug 2023