Search results for "From ACP Journal Club"
In adults with obesity, metabolic–bariatric surgery vs. usual care is associated with lower all-cause mortality
A recent meta-analysis leaves little question that metabolic surgery is lifesaving compared with usual care, yet only 1% of eligible patients are treated with surgery, an ACP Journal Club commentary noted.
https://gastroenterology.acponline.org/archives/2021/09/24/8.htm
24 Sep 2021
In C difficile infection, adding IV bezlotoxumab to standard antibiotics reduced recurrence at 12 weeks
A commentary in ACP Journal Club noted that it would be reasonable to consider fidaxomicin or bezlotoxumab in patients at high risk for recurrent Clostridium difficile infection or in those for whom recurrence could have devastating consequences.
https://gastroenterology.acponline.org/archives/2017/05/26/10.htm
26 May 2017
Colorectal cancer screening offering colonoscopy and FIT vs. colonoscopy alone improved participation
Results of a Polish trial corroborate studies showing that noninvasive tests, such as fecal immunochemical testing (FIT), or screening choice increases colorectal cancer screening participation over colonoscopy, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2021/07/23/6.htm
23 Jul 2021
In adults with severe acute GI bleeding, tranexamic acid did not reduce death due to bleeding at 5 days
Based on findings from a randomized trial, tranexamic acid is unlikely to confer additional benefit beyond the current standard of care in all patients with severe upper or lower GI bleeding, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2020/10/23/10.htm
23 Oct 2020
In eosinophilic esophagitis, budesonide orodispersible tablets maintained remission at 48 wk
While a 0.5-mg dose twice daily may be enough to maintain remission, patients with long-standing symptoms or extensive disease might benefit from a 1-mg dose twice daily, according to an ACP Journal Club commentary.
https://gastroenterology.acponline.org/archives/2021/04/23/8.htm
23 Apr 2021
In irritable bowel syndrome, fecal microbiota transplantation improved symptoms at 3 months
While fecal microbiota transplantation was effective in patients with moderate to severe irritable bowel syndrome in a randomized trial, long-term risks of the therapy remain uncertain, an ACP Journal Club commentary noted.
https://gastroenterology.acponline.org/archives/2020/05/22/10.htm
22 May 2020
H. pylori treatment reduced risk for gastric cancer in patients with a family history of gastric cancer
While results of the trial support a test-and-treat screening approach for Helicobacter pylori in patients with a first-degree relative with gastric cancer, more research is needed before considering universal screening in this population, an ACP Journal Club commentary noted.
https://gastroenterology.acponline.org/archives/2020/06/26/7.htm
26 Jun 2020
In persons with constipation or IBS-C, kiwifruit vs. psyllium increased spontaneous bowel movements
Findings of the randomized trial bolster recommendations of diet manipulation and lifestyle modifications for chronic constipation syndromes, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2023/05/26/7.htm
26 May 2023
Vonoprazan-containing therapy has an H pylori eradication rate >90% and increases eradication vs. standard triple therapy
Results of a systematic review and network meta-analysis support a shift toward a susceptibility-based approach to Helicobacter pylori infection based on principles of antimicrobial stewardship, an ACP Journal Club commentary noted.
https://gastroenterology.acponline.org/archives/2021/10/22/7.htm
22 Oct 2021
Glasgow Blatchford score predicted intervention or death better than 4 other prediction models in upper GI bleeding
Commentary authors writing in ACP Journal Club said the findings add to a growing body of literature that supports the use of the Glasgow Blatchford score for selecting low-risk patients who can safely be discharged from the ED (with a minimal false-negative rate).
https://gastroenterology.acponline.org/archives/2017/04/28/6.htm
28 Apr 2017