Search results for "From ACP Journal Club"
Cholecystectomy reduced major complications vs catheter drainage in high-risk patients with acute cholecystitis
A Dutch trial showed that older patients without life-threatening comorbidities may benefit from early surgical intervention, but the results would be more generalizable if the study had included patients from a broader age range, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2019/03/22/7.htm
22 Mar 2019
Genotypic resistance–guided and medication-guided therapies did not differ for eradicating refractory H pylori
Patients with Helicobacter pylori infection had similar cure rates with resistance-guided and medication-guided therapy, an unexpected finding, according to an ACP Journal Club commentary.
https://gastroenterology.acponline.org/archives/2019/03/22/6.htm
22 Mar 2019
In uncomplicated acute appendicitis, 61% of patients initially treated with antibiotics had not had appendectomy at 5 years
While delay of surgery was not associated with major complications, potential candidates for nonsurgical management of uncomplicated acute appendicitis should be chosen carefully, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2019/01/25/7.htm
25 Jan 2019
In Barrett esophagus, high- vs low-dose esomeprazole improved clinical outcomes; aspirin vs no aspirin did not
The safety of high-dose proton-pump inhibitor therapy is probably acceptable, but the addition of aspirin carries more risk, has less evidence on efficacy, and needs an individualized approach, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2018/12/28/10.htm
28 Dec 2018
In primary biliary cholangitis, adding bezafibrate to ursodeoxycholic acid increased complete biochemical response
Bezafibrate is currently unavailable in the U.S., but fenofibrate can be offered off-label in these patients with close monitoring of adverse effects, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2018/10/26/8.htm
26 Oct 2018
After surgery for stage II or III colorectal cancer, more vs less frequent follow-up did not differ for 5-year mortality
The findings help clarify the ideal process for surveillance of clinical recurrence of colorectal cancer, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2018/10/26/7.htm
26 Oct 2018
In IBS with constipation, plecanatide reduced abdominal pain and increased bowel movements at 12 wk
Clinical judgment will be needed to determine whether the relatively modest improvement in outcomes will be important to patients for whom the drug is considered, according to an accompanying ACP Journal Club commentary.
https://gastroenterology.acponline.org/archives/2018/07/27/9.htm
27 Jul 2018
Colonoscopy outreach increased CRC screening more than FIT outreach; both were better than usual care
Those choosing screening tests may need to start considering the feasibility of achieving all related downstream actions as well as sensitivity, false-positive rates, safety, and cost, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2018/01/26/7.htm
26 Jan 2018
Review: In adult inpatients with mild or moderate acute pancreatitis, early feeding may reduce length of stay
A commentary in ACP Journal Club said the findings reinforce the recommended strategy of attempting early oral feeding in patients with mild acute pancreatitis using a low-fat solid diet as the first meal.
https://gastroenterology.acponline.org/archives/2017/10/27/10.htm
27 Oct 2017
Review: In chronic hepatitis C virus infection, oral direct-acting antivirals have high sustained virologic response
A commentary in ACP Journal Club noted that while screening and treating all patients with chronic hepatitis C virus (HCV) would be cost-effective and probably cost-saving, some payers are still resistant.
https://gastroenterology.acponline.org/archives/2017/07/28/11.htm
28 Jul 2017