Search results for "From ACP Journal Club"
In adults with obesity, metabolic–bariatric surgery vs. usual care is associated with lower all-cause mortality
A recent meta-analysis leaves little question that metabolic surgery is lifesaving compared with usual care, yet only 1% of eligible patients are treated with surgery, an ACP Journal Club commentary noted.
https://gastroenterology.acponline.org/archives/2021/09/24/8.htm
24 Sep 2021
In decompensated cirrhosis, targeted albumin infusions did not improve an in-hospital composite outcome at 15 days
The results of this randomized trial should not discourage clinicians from using albumin for recognized indications, but they do not support targeting an arbitrary serum albumin level, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2021/08/27/7.htm
27 Aug 2021
Colorectal cancer screening offering colonoscopy and FIT vs. colonoscopy alone improved participation
Results of a Polish trial corroborate studies showing that noninvasive tests, such as fecal immunochemical testing (FIT), or screening choice increases colorectal cancer screening participation over colonoscopy, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2021/07/23/6.htm
23 Jul 2021
In patients having transjugular intrahepatic portosystemic shunt, rifaximin prevented overt hepatic encephalopathy
Results from a French trial provide the best available evidence to justify using the expensive antibiotic in patients with hepatic encephalopathy associated with transjugular intrahepatic portosystemic shunt, according to an ACP Journal Club commentary.
https://gastroenterology.acponline.org/archives/2021/07/23/7.htm
23 Jul 2021
In recurrent C difficile infection, oral FMT capsules have a pooled cure rate of 82% (low-quality evidence)
While the findings of a recent study are promising for oral fecal microbiota transplantation (FMT) capsules to treat patients with recurrent Clostridioides difficile infection, more well-designed trials are needed before routine use, an ACP Journal Club commentary noted.
https://gastroenterology.acponline.org/archives/2021/06/25/8.htm
25 Jun 2021
In eosinophilic esophagitis, budesonide orodispersible tablets maintained remission at 48 wk
While a 0.5-mg dose twice daily may be enough to maintain remission, patients with long-standing symptoms or extensive disease might benefit from a 1-mg dose twice daily, according to an ACP Journal Club commentary.
https://gastroenterology.acponline.org/archives/2021/04/23/8.htm
23 Apr 2021
Daily aspirin for primary CVD prevention increased risk for major GI bleeding in healthy older adults
While aspirin is not recommended for primary prevention of cardiovascular disease (CVD) in most adults ages 70 years and older, more research is needed to assess its role in select high-risk populations of older adults, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2021/01/22/6.htm
22 Jan 2021
In adults with severe acute GI bleeding, tranexamic acid did not reduce death due to bleeding at 5 days
Based on findings from a randomized trial, tranexamic acid is unlikely to confer additional benefit beyond the current standard of care in all patients with severe upper or lower GI bleeding, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2020/10/23/10.htm
23 Oct 2020
H. pylori eradication therapy may reduce gastric cancer risk; rifabutin-based therapy effective in industry-sponsored trial
A meta-analysis suggested that, in addition to preventing progression, early Helicobacter pylori eradication therapy reduces gastric cancer risk, and a novel rifabutin-based therapy may offer physicians another option for initiating eradication treatment, an ACP Journal Club commentary on both studies said.
https://gastroenterology.acponline.org/archives/2020/09/25/9.htm
25 Sep 2020
In high-risk patients with acute upper GI bleeding, urgent vs. early endoscopy did not differ for 30-day mortality
While a randomized trial found no better outcomes with endoscopy within six hours of gastroenterology consult, “middle-of-the-night” endoscopy should still be considered for certain higher-risk patients who were excluded from the trial, an ACP Journal Club commentary noted.
https://gastroenterology.acponline.org/archives/2020/08/28/7.htm
28 Aug 2020