Search results for "From ACP Hospitalist"
Study identifies potential predictors of hospital-onset C. difficile infection
In patients colonized with Clostridioides difficile, risk factors for infection included longer length of stay, exposure to multiple classes of antibiotics, use of opioids, and cirrhosis, whereas use of laxatives was associated with a lower risk.
https://gastroenterology.acponline.org/archives/2019/07/26/8.htm
26 Jul 2019
Antibiotic stewardship programs reduce incidence of C. difficile, multidrug-resistant infections, review finds
The systematic review also found that antibiotic stewardship programs were significantly more effective when implemented along with infection control measures.
https://gastroenterology.acponline.org/archives/2017/07/28/12.htm
28 Jul 2017
Selective digestive tract decontamination assessed in ventilated ICU patients
A systematic review found that mechanically ventilated ICU patients had lower in-hospital mortality rates with selective digestive tract decontamination versus standard care or placebo, while a trial found improvement in rates of positive blood cultures and antibiotic-resistant organisms, but not mortality, with the intervention.
https://gastroenterology.acponline.org/archives/2022/11/18/7.htm
18 Nov 2022
Aggressive fluid strategy didn't avert progression to severe pancreatitis
The randomized trial was stopped early due to lack of benefit and significantly higher risk of fluid overload in patients receiving an aggressive fluid resuscitation strategy compared to those getting moderate resuscitation.
https://gastroenterology.acponline.org/archives/2022/09/23/6.htm
23 Sep 2022
Problem of PPIs complicated by COVID-19
While recent studies have suggested that physicians should be careful when using proton-pump inhibitors (PPIs) in patients hospitalized with COVID-19, none have shown a causal relationship between PPIs and COVID-19 infection or severity.
https://gastroenterology.acponline.org/archives/2021/04/23/7.htm
23 Apr 2021
Surgery for malignant small bowel obstruction did not reduce 90-day mortality
A comparison in which some patients with malignant small bowel obstruction were randomized and some chose between surgery and nonsurgical management found no difference in mortality between treatments, but surgery was associated with more symptom improvement.
https://gastroenterology.acponline.org/archives/2023/08/25/9.htm
25 Aug 2023
GI bleeding prophylaxis recommended in high-risk critically ill patients
Proton-pump inhibitors appeared to reduce bleeding risk more than histamine-2 receptor antagonists.
https://gastroenterology.acponline.org/archives/2020/01/24/9.htm
24 Jan 2020
Computerized clinical decision support may help reduce unnecessary C. diff testing
A two-year cohort study of nine academic and six community hospitals in the U.S. found that testing for Clostridioides difficile decreased when the electronic health record stopped a clinician from proceeding with a test order if the patient had already been tested or had recently received laxatives.
https://gastroenterology.acponline.org/archives/2022/02/25/7.htm
25 Feb 2022
Facility-level antibiotic use associated with C. difficile rates in long-term care
Importation of Clostridium difficile was three times more common in long-term care than in acute care, leading the study authors to recommend better coordination of infection control across settings.
https://gastroenterology.acponline.org/archives/2017/06/23/7.htm
23 Jun 2017
Studies examine impact of hospital policies on C. difficile infection rates
While one study found that participation in an antibiotic stewardship program from the Agency for Healthcare Research and Quality led to reductions in hospital-onset Clostridioides difficile infection rates, a simulation study found that visitor contact precautions may not be as helpful.
https://gastroenterology.acponline.org/archives/2021/03/26/7.htm
26 Mar 2021