Search results for "From ACP Hospitalist"
Patients with discordant C. difficile test results had lower mortality with treatment
Patients who were positive for Clostridioides difficile on nucleic acid amplification testing but negative on toxin immunoassay had similar 30-day mortality to those with positive results on both tests, according to a review of observational studies.
https://gastroenterology.acponline.org/archives/2023/09/22/7.htm
22 Sep 2023
Catching C. diff cases, not colonization
Researchers have found innovative ways to improve hospital systems for diagnosing Clostridioides difficile.
https://gastroenterology.acponline.org/archives/2023/08/25/8.htm
25 Aug 2023
Surgery for malignant small bowel obstruction did not reduce 90-day mortality
A comparison in which some patients with malignant small bowel obstruction were randomized and some chose between surgery and nonsurgical management found no difference in mortality between treatments, but surgery was associated with more symptom improvement.
https://gastroenterology.acponline.org/archives/2023/08/25/9.htm
25 Aug 2023
Two-step testing for Clostridioides difficile appears safe in multicenter study
Using an enzyme immunoassay after a positive nucleic acid amplification test was associated with a decrease in hospital-onset Clostridioides difficile infections and a reduction in related antibiotic use but no change in emergent colectomies.
https://gastroenterology.acponline.org/archives/2023/06/23/7.htm
23 Jun 2023
Mandatory approval process for C. diff testing linked to lower hospital-onset infection rates
An intervention that required mandatory approval from an infectious diseases physician before testing for Clostridioides difficile was associated with a greater than 50% decrease in hospital-onset C. difficile infection rates at one hospital.
https://gastroenterology.acponline.org/archives/2023/05/26/6.htm
26 May 2023
Most asymptomatic C. difficile carriers in health care settings did not progress to infection
In a study at three U.S. hospitals and affiliated long-term care facilities, most patients who were found to be carriers of Clostridioides difficile had cleared the bacteria on subsequent testing, and only 13.4% were subsequently diagnosed with infection.
https://gastroenterology.acponline.org/archives/2023/03/24/8.htm
24 Mar 2023
Stopping the cycle of C. diff
Microbiota therapies offer exciting potential to reduce the burden of recurrent Clostridioides difficile infection, experts say.
https://gastroenterology.acponline.org/archives/2023/02/24/8.htm
24 Feb 2023
EBV monitoring after liver transplant may help reduce incidence of PTLD
A strategy that monitored Epstein-Barr virus (EBV) viral load after liver transplant in adults was associated with decreased incidence of post-transplant lymphoproliferative disease (PTLD), a retrospective Dutch study found.
https://gastroenterology.acponline.org/archives/2023/01/27/8.htm
27 Jan 2023
Selective digestive tract decontamination assessed in ventilated ICU patients
A systematic review found that mechanically ventilated ICU patients had lower in-hospital mortality rates with selective digestive tract decontamination versus standard care or placebo, while a trial found improvement in rates of positive blood cultures and antibiotic-resistant organisms, but not mortality, with the intervention.
https://gastroenterology.acponline.org/archives/2022/11/18/7.htm
18 Nov 2022
Glycogenic hepatopathy
A 21-year-old man with type 1 diabetes presented to the hospital with nausea, vomiting, and abdominal pain. Physical exam showed hepatosplenomegaly.
https://gastroenterology.acponline.org/archives/2022/09/23/7.htm
23 Sep 2022