Search results for "Highlights"
In adults using oral anticoagulants, PPI use may be associated with lower risk for upper GI bleeding
An ACP Journal Club commentary on the meta-analysis stressed the importance of assessing patients' underlying risk for GI bleeding and using overall clinical risk to guide shared decision making in those at higher risk or with lower baseline bleeding tolerance.
https://gastroenterology.acponline.org/archives/2022/11/18/9.htm
18 Nov 2022
AGA releases new guidance on coagulation disorders in patients with cirrhosis
A clinical practice guideline from the American Gastroenterological Association (AGA) suggested against extensive preprocedural testing in patients with stable cirrhosis who are undergoing routine GI procedures, among other recommendations.
https://gastroenterology.acponline.org/archives/2021/11/19/3.htm
19 Nov 2021
IV iron regimens compared for serum phosphate effects in patients with IBD
Ferric carboxymaltose and ferric derisomaltose worked well to resolve anemia from inflammatory bowel disease (IBD), but the former was associated with low serum phosphate levels, according to an industry-funded trial.
https://gastroenterology.acponline.org/archives/2022/09/23/2.htm
23 Sep 2022
PPIs not associated with mortality risk for most causes, study finds
While patients who took proton-pump inhibitors (PPIs) had significantly higher risks of all-cause mortality and mortality due to cancer, cardiovascular diseases, respiratory diseases, and digestive diseases, lag times of up to six years attenuated these associations so they were no longer statistically significant.
https://gastroenterology.acponline.org/archives/2022/07/22/1.htm
22 Jul 2022
Antibiotics may not reduce length of stay in patients hospitalized for uncomplicated diverticulitis
A randomized trial found that median length of hospital stay was 40.0 hours in the antibiotic group and 45.8 hours in the placebo group, with no significant between-group differences in adverse events or readmissions.
https://gastroenterology.acponline.org/archives/2020/04/24/2.htm
24 Apr 2020
Colonoscopy surveillance every 3 years may be sufficient after polypectomy
A multicenter randomized trial in Japan found that a single surveillance colonoscopy three years postpolypectomy and two surveillance colonoscopies at one and three years were similarly accurate for detecting clinically important neoplastic lesions.
https://gastroenterology.acponline.org/archives/2020/11/20/2.htm
20 Nov 2020
Weight loss interventions may improve biomarkers of liver disease in NAFLD
In a meta-analysis of 22 studies in patients with nonalcoholic fatty liver disease (NAFLD), weight loss interventions were associated with improvements in alanine aminotransferase level, liver steatosis, histologic NAFLD activity score, and nonalcoholic steatohepatitis.
https://gastroenterology.acponline.org/archives/2019/07/26/3.htm
26 Jul 2019
Best practice advice offered for diagnosis, management of seronegative enteropathy
The American Gastroenterological Association said that diagnosis of seronegative celiac disease, the most common cause of seronegative enteropathy, can be complicated by misinterpretation of histological findings, insufficient serological testing, IgA deficiency, and premature initiation of a gluten-free diet.
https://gastroenterology.acponline.org/archives/2020/10/23/3.htm
23 Oct 2020
Wireless monitoring identified patients who could discontinue PPIs
Patients with reflux symptoms and inadequate response to proton-pump inhibitors (PPIs) discontinued the drugs for a week and then had their acid exposure time measured by a wireless pH capsule in a recent study.
https://gastroenterology.acponline.org/archives/2020/09/25/3.htm
25 Sep 2020
Anti-TNF therapy did not reduce IBD hospitalizations or intestinal resections in Ontario
Infliximab may have been used inappropriately in Crohn's disease and underused in ulcerative colitis, according to the authors of an analysis of hospitalizations, intestinal resections, and drug costs related to inflammatory bowel disease (IBD).
https://gastroenterology.acponline.org/archives/2019/06/28/3.htm
28 Jun 2019