Search results for "Constipation"
MKSAP Quiz: 6-month history of constipation
A 52-year-old man is evaluated for a 6-month history of constipation. He has bowel movements once every 5 days, low back pain after 2 days without a bowel movement, and straining during defecation. He reports no abdominal pain. After a physical exam and lab tests, what is the most appropriate management?
https://gastroenterology.acponline.org/archives/2023/11/17/4.htm
17 Nov 2023
In persons with constipation or IBS-C, kiwifruit vs. psyllium increased spontaneous bowel movements
Findings of the randomized trial bolster recommendations of diet manipulation and lifestyle modifications for chronic constipation syndromes, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2023/05/26/7.htm
26 May 2023
Response to linaclotide for IBS constipation can still appear after four weeks
An industry-funded analysis of four randomized trials of linaclotide for irritable bowel syndrome (IBS) with constipation found that improvement in abdominal and bowel symptoms occurred after four weeks of treatment in 1 in 6 and 1 in 10 patients, respectively.
https://gastroenterology.acponline.org/archives/2022/12/23/6.htm
23 Dec 2022
Guidance issued on pharmacologic treatment of chronic idiopathic constipation
The joint clinical practice guideline from the American Gastroenterological Association and the American College of Gastroenterology reviewed evidence on fiber, osmotic laxatives, stimulant laxatives, secretagogues, and a serotonin type 4 agonist.
https://gastroenterology.acponline.org/archives/2023/05/26/1.htm
26 May 2023
Recommendations for pharmacologic management of IBS with diarrhea, constipation
New guidelines suggest that there are several effective drugs available for irritable bowel syndrome (IBS), but a more detailed analysis indicates that the best treatments increase the rate of response by only 15% versus placebo, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2022/11/18/8.htm
18 Nov 2022
Systematic review compares over-the-counter treatments for chronic constipation
Polyethylene glycol and senna had good evidence for their use as first-line laxatives, while moderate evidence supported fiber supplements, fruits, stimulant laxatives, and magnesium-based products.
https://gastroenterology.acponline.org/archives/2021/06/25/3.htm
25 Jun 2021
Severe COVID-19 associated with more IBS, less constipation
A prospective multicenter study found that patients hospitalized for COVID-19 had significantly higher rates of irritable bowel syndrome (IBS) and fewer problems with constipation at 12 months than controls.
https://gastroenterology.acponline.org/archives/2022/12/23/1.htm
23 Dec 2022
Thalidomide reduced bleeding in patients with small-intestinal angiodysplasia
A total of 68.6% of patients who were randomized to 100 mg of thalidomide daily (taken in four doses a day) had a reduction of at least 50% in bleeding episodes in the year after treatment compared to 16% of those on placebo.
https://gastroenterology.acponline.org/archives/2023/12/22/2.htm
22 Dec 2023
MKSAP quiz: Persistent constipation for 2 years
This month's quiz asks readers to determine the most appropriate treatment for persistent constipation in a 60-year-old woman taking chronic opioid analgesic therapy for reflex sympathetic dystrophy syndrome.
https://gastroenterology.acponline.org/archives/2018/12/28/4.htm
28 Dec 2018
In symptomatic adults undergoing high-resolution manometry, long-term opioid use was linked to esophageal dysmotility
The results of a recent meta-analysis highlight the need for clinicians to widen their perspective on the risks of opioids to include both upper and lower GI motility disorders, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2023/12/22/8.htm
22 Dec 2023