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More liver transplants occurring in patients with alcohol-associated liver disease

The increase from 2002 to 2016 can partly be explained by reductions in hepatitis C-related transplants but may also indicate changing perspectives on abstinence requirements, study authors said.
https://gastroenterology.acponline.org/archives/2019/01/25/4.htm
25 Jan 2019

MKSAP Quiz: Management of hepatic encephalopathy

This month's quiz asks readers to determine the most appropriate course of management for a 56-year-old man presenting with altered mental status and a history of cirrhosis and anxiety.
https://gastroenterology.acponline.org/archives/2019/11/22/4.htm
22 Nov 2019

ACIP updates hepatitis A vaccination recommendations

The Advisory Committee on Immunization Practices (ACIP) changed its recommendations regarding vaccination of patients with chronic liver disease, pregnant women, and those treated with blood products for clotting disorders, among other revisions.
https://gastroenterology.acponline.org/archives/2020/07/24/1.htm
24 Jul 2020

Alcohol-related liver disease more likely to be diagnosed at advanced stages, study finds

On the other hand, viral hepatitis-related disease and nonalcoholic fatty liver disease are more likely to be treated early, due in part to the development of effective drugs for the former and increased awareness of the latter.
https://gastroenterology.acponline.org/archives/2019/02/22/3.htm
22 Feb 2019

Spotlight on screening in primary care

Patient-specific reminders for clinicians performed best for increasing colorectal cancer screening in a French study, while an EHR alert appeared to successfully increase hepatitis C virus screening rates for baby boomers in a U.S. health care system.
https://gastroenterology.acponline.org/archives/2017/09/22/5.htm
22 Sep 2017

Prophylactic HCV treatment with direct-acting antivirals appears safe in noninfected kidney recipients

Researchers studied 10 HCV-negative recipients of 10 HCV-positive donor kidneys in an open-label, nonrandomized trial.
https://gastroenterology.acponline.org/archives/2018/03/23/3.htm
23 Mar 2018

Project ECHO model appears cost-effective for HCV diagnosis, treatment

The incremental cost-effectiveness ratio with Project ECHO versus usual care was $10,351 per QALY, with 95.6% of iterations falling below a willingness-to-pay threshold of $50,000 per QALY and more than 99.9% falling below a willingness-to-pay threshold of $100,000 per QALY.
https://gastroenterology.acponline.org/archives/2017/11/28/3.htm
28 Nov 2017

Spotlight on mortality trends in liver disease

One study looked at 10-year U.S. mortality trends related to chronic liver diseases, while another assessed mortality from cirrhosis and liver cancer in the U.S. from 1999 to 2016.
https://gastroenterology.acponline.org/archives/2018/07/27/5.htm
27 Jul 2018

Nearly all patients in study achieved sustained virologic response after 12 weeks of new HCV treatment

The drug combination appeared effective in adults with HCV genotypes 1, 2, 4, 5, or 6 infection and compensated cirrhosis in the industry-funded trial.
https://gastroenterology.acponline.org/archives/2017/08/25/3.htm
25 Aug 2017

HCV treatment by NPs, PCPs appears safe, effective as that provided by subspecialists

Reversing insurance restrictions that limit prescribing of direct-acting antivirals might allow rapid escalation of safe, effective therapy for hepatitis C virus (HCV) infection and could improve the care of patients, study authors noted.
https://gastroenterology.acponline.org/archives/2017/08/25/6.htm
25 Aug 2017

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