Search results for "Highlights"
Review finds antibiotics associated with heightened risk of inflammatory bowel disease
There was a positive, nonlinear dose-response association between the number of antibiotic prescriptions patients received and their inflammatory bowel disease risk, according to a systematic review.
https://gastroenterology.acponline.org/archives/2024/03/22/2.htm
22 Mar 2024
Tranexamic acid may help with upper GI bleeding after esophageal variceal ligation
Tranexamic acid significantly reduced upper GI bleeding after esophageal variceal ligation, but mortality rates were similar to those with placebo, a trial in India found.
https://gastroenterology.acponline.org/archives/2024/03/22/3.htm
22 Mar 2024
AGA issues guidance on diet, nutrition in IBD
A new clinical practice update from the American Gastroenterological Association (AGA) covers the role of diet and nutritional therapies in managing inflammatory bowel disease (IBD) and identifying and treating malnutrition in IBD patients.
https://gastroenterology.acponline.org/archives/2024/02/23/1.htm
23 Feb 2024
Spotlight on treatment response in Crohn's disease
Recent studies evaluated early versus late response to biologic therapy, treatment response and infection risk, and endoscopic outcomes.
https://gastroenterology.acponline.org/archives/2024/01/26/5.htm
26 Jan 2024
In symptomatic adults undergoing high-resolution manometry, long-term opioid use was linked to esophageal dysmotility
The results of a recent meta-analysis highlight the need for clinicians to widen their perspective on the risks of opioids to include both upper and lower GI motility disorders, an ACP Journal Club commentary said.
https://gastroenterology.acponline.org/archives/2023/12/22/8.htm
22 Dec 2023
For ulcerative colitis, ustekinumab safe, effective through 4 years, industry study finds
Most patients who had symptomatic remission of their ulcerative colitis on the drug maintained it without corticosteroids, an extension of a randomized trial found.
https://gastroenterology.acponline.org/archives/2023/12/22/3.htm
22 Dec 2023
Thalidomide reduced bleeding in patients with small-intestinal angiodysplasia
A total of 68.6% of patients who were randomized to 100 mg of thalidomide daily (taken in four doses a day) had a reduction of at least 50% in bleeding episodes in the year after treatment compared to 16% of those on placebo.
https://gastroenterology.acponline.org/archives/2023/12/22/2.htm
22 Dec 2023
Noninvasive methods show promise for CRC screening
A DNA blood-based test had approximately 83% sensitivity for colorectal cancer (CRC) and 13% sensitivity for advanced precancerous lesions in one industry-funded study, while a next-generation multitarget stool DNA test showed higher sensitivity but lower specificity for CRC and advanced precancerous lesions than fecal immunochemical testing in another.
https://gastroenterology.acponline.org/archives/2024/03/22/1.htm
22 Mar 2024
No-biopsy approach can diagnose celiac disease in select adults
IgA anti-tissue transglutaminase levels of at least 10 times the upper limit of normal have a sensitivity of 51% and specificity of 100% for predicting celiac disease in adults referred to secondary care, a meta-analysis found.
https://gastroenterology.acponline.org/archives/2024/01/26/1.htm
26 Jan 2024
Concurrent cholinesterase inhibitors, NSAIDs linked to peptic ulcer risk
Risk of peptic ulcers increased ninefold when patients ages 65 years and older took cholinesterase inhibitors and NSAIDs concurrently, a Swedish study found, leading the authors to suggest that the combination be considered potentially inappropriate for older patients.
https://gastroenterology.acponline.org/archives/2023/11/17/2.htm
17 Nov 2023